Job Description

Frontier Medicines is seeking a highly motivated individual to fill the position of Executive Director/Vice President, Medicinal Chemistry. This person will play a leading role in leveraging our chemoproteomic platform to tackle high value but difficult to drug disease targets and in further developing our chemistry capabilities. The team is focused on the discovery of new medicines to treat cancers and other serious disorders. The successful candidate will be a seasoned drug hunter with a track record of success in leading teams to discovering and advancing clinical candidates and approved drugs. To be successful, this leader will need to cultivate a strong team of medicinal chemists that excels at solving tough drug discovery challenges in novel and/or hard-to-drug chemical spaces. The position will report to the Chief Scientific Officer and will be located in South San Francisco. 

The Executive Director/Vice President, Medicinal Chemistry is a key contributor to Frontier Medicines’ success and will be interacting with senior leaders, including the CEO, routinely. This is an opportunity to join and work in a highly collaborative and energetic team in a startup environment with short communication lines across functions and departments.

Requirements

What will you be doing?

• Define and execute on the vision and strategy for drug discovery that results in the sustained delivery of high quality, differentiated small molecule drugs. 
• Build a highly effective team of medicinal chemistry leaders and scientists that can succeed against a broad portfolio of targets across a range of modalities and therapeutic areas.
• Engage with project teams to ensure critical success factors have been identified and resource the teams to succeed in meeting those objectives.
• Directly mentor leaders, teams and scientists in your organization to embrace and implement AI, and new technologies that accelerate the delivery of new medicines.
• Drive preclinical development of lead assets to achieve project deliverables. 
• Manage contract research relationships to consistently deliver high quality molecules
• Develop intellectual property and interact effectively with partners in tech transfer/legal to advance the company’s IP strategy.
• Effectively communicate research updates and provide strategic input with colleagues, stakeholders, Board of Directors and Scientific Advisory Board as needed. 
• Engage external parties as appropriate in business development activities. 

What we are looking for:

• Ph.D. in organic or medicinal chemistry with at least 15 years of relevant post-graduate experience in pharma/biotech. 
• A proven track record of success in leading successful medicinal chemistry teams to advance strong drug candidates to the clinic.
• Extensive experience in structure-based-design, fragment -based drug discovery, ADME PK optimization and achieving challenging target product profiles.
• Delivery of impactful patents and publications in medicinal chemistry. 
• Project leadership experience. 
• Experience in overseeing and directing day-to-day scientific activities of junior staff and CRO scientists. 
• A commitment to excellence, including ensuring that team members maintain detailed records and superb data organization. 
• Legally authorized to work in the US. 

Benefits

• Health Care Plan (Medical, Dental & Vision)
• Retirement Plan (401k, IRA)
• Life Insurance (Basic, Voluntary & AD&D)
• Paid Time Off (Vacation, Sick & Public Holidays)
• Family Leave (Maternity, Paternity)
• Short Term & Long Term Disability
• Training & Development
• Free Food & Snacks
• Wellness Resources
• Stock Option Plan

At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $265,000 - $350,000. Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.

This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.

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